Signal Transduction Reagents and Kits
Enzo Life Sciences Mca-RPPGFSAFK(Dnp) (1 mg)
Protease substrate. Fluorogenic substrate for ECE-1 and ECE-2, ACE1 and ACE2, neprilysin, MMP-2 and MMP-9, thimet oligopeptidase, as well as cathepsin A, cathepsin X/Z, BACE, and insulinase, but not MMP-1.Mca fluorescence is quenched by the Dnp group until cleavage separates them. Ex.: 328nm, Em.: 393nm, although the following Ex/Em have also been used: 320-340/400-420. This substrate is useful for inhibitor screening and kinetic analysis. MW: 1388.5. Formulation: Lyophilized. Purity: ≥98% (HPLC). Sequence Mca-Arg-Pro-Pro-Gly-Phe-Ser-Ala-Phe-Lys(Dnp)-OH[Mca=(7-methoxycoumarin-4-yl)acetyl;Dnp=2,4-dinitrophenyl]. Appearance: White to off-white solid. Solubility: Soluble in DMSO to at least 10mM. Long Term Storage: -20°C. Use/Stability: Store, as supplied, at -20°C for up to 1 year. Store solutions at -20°C for up to 3 months. Handling: Protect from light and moisture.
Medchemexpress LLC Malic enzyme inhibitor ME1 | 522649-59-8 | 99.7% | 351.40 g·mol⁻¹ | C20H21N3O3 | 50MG
Malic enzyme inhibitor ME1 is a small-molecule, selective inhibitor of cytosolic malic enzyme (ME1) used for biochemical and cellular research. It exhibits potent inhibition of ME1 (IC50 = 0.15 μM) and is supplied as a white to off-white solid with high purity and defined storage recommendations.
- Potent ME1 inhibition (IC50 = 0.15 μM).
- High purity suitable for biochemical assays (99.7%).
- Supplied as a solid, white to off-white.
- Highly soluble in DMSO; may require sonication and warming.
- Stable when stored under recommended conditions in powder or solution.
![CPC Scientific 4-(4-Dimethylaminophenylazo)benzoyl-Tyr-Val-Ala-Asp-Ala-Pro-Val-5-[(2-aminoethyl)amino]-naphthalene-1-sulfonic acid 1MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/VN00111436-SUBS-016.PNG-250.jpg)
CPC Scientific 4-(4-Dimethylaminophenylazo)benzoyl-Tyr-Val-Ala-Asp-Ala-Pro-Val-5-[(2-aminoethyl)amino]-naphthalene-1-sulfonic acid 1MG
SEQUENCE: 4-(4-Dimethylaminophenylazo)benzoyl-Tyr-Val-Ala-Asp-Ala-Pro-Val-5-[(2-aminoethyl)amino]-naphthalene-1-sulfonic acidONE-LETTER SEQUENCE: 4-(4-Dimethylaminophenylazo)benzoyl-YVADAPV-5-[(2-aminoethyl)amino]-naphthalene-1-sulfonic acidMOLECULAR FORMULA: C61H76N12O14S1MOLECULAR WEIGHT: 1233.39STORAGE CONDITIONS: -20 5 CCAS REGISTRY NUMBER: [161877-70-9]SYNONYMS: Caspase 1 (ICE) Substrate; dabcyl-yvadapv-edans; dabcyl-tyr-val-ala-asp-ala-pro-val-edans; ICE Substrate Ii; il-1-beta Converting Enzyme Substrate Ii; il-1b Converting Enzyme Substrate Ii; 4-(4-dimethylaminophenylazo)benzoyl-tyr-val-ala-asp-ala-pro-val-5-[(2-aminoethyl)amino]-naphthalene-1-sulfonic acid; 4-(4'-dimethylaminophenylazo)benzoyl-tyrosyl-valyl-alanyl-aspartyl-alanyl-prolyl-valyl-5((2-aminoethyl)amino)naphthalene-1-sulfonic acidRESEARCH AREA: ApoptosisREFERENCES:M.W. Pennington et al., Peptide Res., 7, 72 (1994)M. Los et al., Nature 375, 81 (1995)SKU(s): SUBS-016A, SUBS-016B
Sigma Aldrich Fine Chemicals Biosciences Zolmitriptan Related Compound H United States Pharmacopeia (USP) Reference Standard | 1116-77-4 | MFCD00671479 | 50MG
Zolmitriptan Related Compound H United States Pharmacopeia (USP) Reference Standard | Mol Wt: 189.3 | 1116-77-4 | MFCD00671479 | 50MG
Enzo Life Sciences STA-21, (1mg), CAS Number: 28882-53-3
STAT inhibitor. STA-21 is a novel Stat3-selective inhibitor. It inhibits Stat3 dimerization and DNA binding as well as Stat3-dependent luciferase reporter activity. Alternative Name: (S)-Ochromycinone, Deoxytetrangomycin. Formula: C19H14O4. MW: 306.3. CAS Number: 28882-53-3. Purity: ≥98% (HPLC). Appearance: White to yellow solid. Solubility: Soluble in DMSO (20mg/ml). Use/Stability: Store solutions at -20°C for up to 3 months. Long Term Storage: -20°C
Revvity Health Sciences Inc HTRF Human IL-17A / IL17RA Binding Kit Standard
HTRF Human IL-17A / IL17RA Binding Kit Standard
Echelon Biosciences Research Labs 3S-PTDINS(3,4,5)P3 DIC16 500 ug
PtdIns(3,4,5)P3 3-phosphothioate, diC16 (3S-PtdIns(3,4,5)P3, diC16) is a water-soluble, synthetic PI(3,4,5)P3 analog in which the 3-phosphate has been rendered metabolically stable as a phosphorothioate. P-3S908 shows 90% inhibition of PTEN at 0.4M. This item is non returnable
Enzo Life Sciences PD-98059, (5mg), CAS Number: 167869-21-8
MEK inhibitor. PD-98059 is a potent and selective inhibitor of MAP kinase kinase (MEK). It selectively blocks the activation of MEK thereby inhibiting the phosphorylation and the activation of MAP kinase. PD-98059 is cell permeable. In PC12 pheochromocytoma cells, it completely blocked the increase in MAP kinase activity produced by NGF, IC50=2µM. Enhances self-renewal of embryonic stem cells PD-98059 is an invaluable tool to help elucidate the role of the MAPK cascade in a variety of biological systems. Inhibits cell growth and proliferation in acute myelogenous leukemia cell lines by causing cell arrest. Formula: C16N13NO3. MW: 267.3. CAS Number: 167869-21-8. Purity: ≥95% (HPLC). Appearance: Pale yellow solid. Solubility: Soluble in DMSO (6.5mg/ml); 25mg/ml in anhydrous DMSO), methanol, dichlormethane and 100% ethanol (0.6mg/ml). Long Term Storage: -20°C
Echelon Biosciences Research Labs EICOSANOYL LPA 1 mg
Arachidoyl LPA, 20:0 LPA (aka Eicosanoyl LPA) is an analog of lysophosphatidic acid (LPA), a lysophospholipid involved in cell proliferation. Lysophosphatidic Acid (LPA) is a small lysophospholipid involved in diverse cellular processes such as cell proliferation, chemotaxis, platelet aggregation, wound healing, angiogenesis, tumor invasion, and smooth muscle contraction. LPA binds to several G-coupled protein receptors to initiate its biological functions. In cancer, LPA primarily promotes cell survival, migration and invasion. May contain up to 5-10% of the 2-acyl isomer due to acyl transfer. This item is non returnable
Enzo Life Sciences Lysophosphatidic acid, (5mg), CAS Number: 325465-93-8
LPA receptor ligand. Lysophosphatidic acid (LPA) is a multifunctional intercellular phospholipid messenger. LPA stimulates the growth of a variety of cells including fibroblasts, vascular smooth muscle cells, endothelial cells and keratinocytes. It acts as a proliferative and anti-apoptotic factor. Ligand for LPA1 (EDG-2), LPA2 (EDG-4) and LPA3 (EDG-7) receptors. It also inhibits differentiation of neural stem cells into neurons. Alternative Name: 1-Oleoyl-lysophosphatidic acid . sodium salt. Formula: C21H40O7P . Na. MW: 458.5. CAS Number: 325465-93-8. Purity: ≥98% (TLC). Appearance: Waxy solid. Solubility: Soluble in water (5 mg/mL with sonication) or DMSO (0.5 mg/mL warm). Use/Stability: Store as supplied at -20°C for up to 1 year. Store solutions at -20°C for up to 1 month. Long Term Storage: -20°C
Enzo Life Sciences BML-210 (1mg). CAS: 537034-17-6
HDAC inhibitor developed at Enzo Life Sciences. Inhibits HDAC activity in HeLa nuclear extracts (IC50=5-10µM). Purity: ≥98% (TLC). Solubility: Soluble in DMSO (25mg/ml) or 100% ethanol (10mg/ml, warm). Long Term Storage: -20°C.
Revvity Health Sciences Inc HTRF Human Phospho-STAT3 (Tyr705) Detection Kit, 50,000 Assay Points
HTRF Human Phospho-STAT3 (Tyr705) Detection Kit, 50,000 Assay Points
Apexbio Technology LLC highly selective, potent and cell-permeable p38 MAPK inhibitor 152121-30-7. MFCD00941964
highly selective, potent and cell-permeable p38 MAPK inhibitor 152121-30-7. MFCD00941964
Carnabio Usa Inc CK1G1(CSNK1G1)/5UG/FULL-LENGTH
CK11(CSNK1G1), Full-length, Wild type, Amino Acid 1-422, NP_071331.2, Expressed in Insect (sf21); 5microg
Enzo Life Sciences Lysophosphatidic acid (25mg). CAS: 325465-93-8
Lysophosphatidic acid (LPA) is a multifunctional intercellular phospholipid messenger. LPA stimulates the growth of a variety of cells including fibroblasts, vascular smooth muscle cells, endothelial cells and keratinocytes. It acts as a proliferative and anti-apoptotic factor. Ligand for LPA1 (EDG-2), LPA2 (EDG-4) and LPA3 (EDG-7) receptors. It also inhibits differentiation of neural stem cells into neurons. Alternative name: 1-Oleoyl-lysophosphatidic acid . sodium salt. Purity: ≥98% (TLC). Solubility: Soluble in water (5 mg/mL with sonication) or DMSO (0.5 mg/mL warm). Long Term Storage: -20°C.